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Editorial Board
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IBMS Board of Directors
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IBMS Corporate Partners
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xi
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IBMS Membership Application
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xii
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| Articles |
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Article Title |
Author(s) |
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Mechanical Stretch Induced Calcium Efflux from Bone Matrix Stimulates Osteoblasts
Abstract: The mechanisms by which bone cells sense critically loaded regions of bone are still a matter of ongoing debate. Animal models to investigate response to microdamage involve post mortem immu...
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Xuanhao Sun,
Eric McLamore,
Vipuil Kishore,
Kateri Fites,
Mikhail Slipchenko,
D. Marshall Porterfield,
Ozan Akkus
et al.
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581-591
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Molecular characterisation of the Hyp deletion and an improved assay for its detection
24 January 2012
Abstract: The Hyp mouse is a commonly used model for the study of the phosphate wasting disease X-linked hypophosphataemia. The defect in this mouse line is a deletion that includes exons 16 to 22 of ...
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Campbell R. Sheen,
Genay O.W. Pilarowski,
Wei Wang,
Jose Luis Millan
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592-595
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Changes in intracortical microporosities induced by pharmaceutical treatment of osteoporosis as detected by high resolution micro-CT
19 January 2012
Abstract: Bone's microporosities play important biologic and mechanical roles. Here, we quantified 3D changes in cortical osteocyte-lacunae and other small porosities induced by estrogen withdrawal an...
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Steven M. Tommasini,
Andrea Trinward,
Alvin S. Acerbo,
Francesco De Carlo,
Lisa M. Miller,
Stefan Judex
et al.
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596-604
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Determinants of vitamin D status in a general population of Danish adults
24 January 2012
Abstract: Background and aims: Danish legislation regarding food fortification has been very restrictive and vitamin D deficiency is thought to be common in Denmark due to inadequate dietary intakes a...
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B. Thuesen,
L. Husemoen,
M. Fenger,
J. Jakobsen,
P. Schwarz,
U. Toft,
L. Ovesen,
T. Jørgensen,
A. Linneberg
et al.
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605-610
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Further improvements on the factors affecting bone mineral density measured by quantitative micro-computed tomography
23 December 2011
Abstract: The effects of imaging parameters and special configuration of objects within the reconstruction space on the micro computed tomography (μCT) based mineral density have been explored, and a ...
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Vahid Entezari,
Vartan Vartanians,
David Zurakowski,
Nipun Patel,
Roberto J. Fajardo,
Ralph Müller,
Brian D. Snyder,
Ara Nazarian
et al.
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611-618
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GSK-3 inhibition by an orally active small molecule increases bone mass in rats
19 December 2011
Abstract: Glycogen synthase kinase 3β (GSK-3β) actions are central in the canonical Wnt pathway, important in many biological processes and a potential drug target for treating several diseases. It is...
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Richard Marsell,
Gregor Sisask,
Yvonne Nilsson,
Anna K. Sundgren-Andersson,
Ulf Andersson,
Sune Larsson,
Olle Nilsson,
Östen Ljunggren,
Kenneth B. Jonsson
et al.
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619-627
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Bone turnover markers in peripheral blood and marrow plasma reflect trabecular bone loss but not endocortical expansion in aging mice
26 December 2011
Abstract: We examined age-related changes in biochemical markers and regulators of osteoblast and osteoclast activity in C57BL/6 mice to assess their utility in explaining age-related changes in bone....
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Mohammad Shahnazari,
Denise Dwyer,
Vivian Chu,
Frank Asuncion,
Marina Stolina,
Michael Ominsky,
Paul Kostenuik,
Bernard Halloran
et al.
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628-637
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Longitudinal effects of fat and lean mass on bone accrual in infants
19 December 2011
Abstract: There are conflicting reports on the influence of lean and fat mass on bone accrual during childhood. No infant's studies have been reported that describe the influence of changes in body co...
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Ramu G. Sudhagoni,
Howard E. Wey,
Gemechis D. Djira,
Bonny L. Specker
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638-642
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Quantitative second-harmonic generation microscopy for imaging porcine cortical bone: Comparison to SEM and its potential to investigate age-related changes
22 December 2011
Abstract: We propose the use of second-harmonic generation (SHG) microscopy for imaging collagen fibers in porcine femoral cortical bone. The technique is compared with scanning electron microscopy (S...
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Raghu Ambekar,
Michael Chittenden,
Iwona Jasiuk,
Kimani C. Toussaint
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643-650
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Botulinum toxin in masticatory muscles: Short- and long-term effects on muscle, bone, and craniofacial function in adult rabbits
21 December 2011
Abstract: Paralysis of the masticatory muscles using botulinum toxin (BTX) is a common treatment for cosmetic reduction of the masseters as well as for conditions involving muscle spasm and pain. The ...
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Katherine L. Rafferty,
Zi Jun Liu,
Wenmin Ye,
Alfonso L. Navarrete,
Thao Tuong Nguyen,
Atriya Salamati,
Susan W. Herring
et al.
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651-662
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TGF-β regulates sclerostin expression via the ECR5 enhancer
26 December 2011
Abstract: Wnt signaling is critical for skeletal development and homeostasis. Sclerostin (Sost) has emerged as a potent inhibitor of Wnt signaling and, thereby, bone formation. Thus, strategies to red...
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Gabriela G. Loots,
Hansjoerg Keller,
Olivier Leupin,
Deepa Murugesh,
Nicole M. Collette,
Damian C. Genetos
et al.
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663-669
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Ucma is not necessary for normal development of the mouse skeleton
03 January 2012
Abstract: Ucma (Upper zone of growth plate and Cartilage Matrix Associated protein) is a highly conserved tyrosine-sulphated secreted protein of Mw 17kDa, which is expressed by juvenile chondrocytes. ...
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Nicole Eitzinger,
Cordula Surmann-Schmitt,
Michael Bösl,
Georg Schett,
Klaus Engelke,
Andreas Hess,
Klaus von der Mark,
Michael Stock
et al.
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670-680
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Dietary silicon interacts with oestrogen to influence bone health: Evidence from the Aberdeen Prospective Osteoporosis Screening Study
26 December 2011
Abstract: Background: Silicon (Si), as Si(OH)4, is derived mainly from plant-based foods. Dietary Si is associated with bone mineral density (BMD) in premenopausal but not postmenopausal women. Object...
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Helen M. Macdonald,
Antonia C. Hardcastle,
Ravin Jugdaohsingh,
William D. Fraser,
David M. Reid,
Jonathan J. Powell
et al.
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681-687
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Increased proportion of hypermineralized osteocyte lacunae in osteoporotic and osteoarthritic human trabecular bone: Implications for bone remodeling
30 December 2011
Abstract: Hypermineralized osteocyte lacunae (micropetrosis) have received little research attention. While they are a known aspect of the aging human skeleton, no data are available for pathological ...
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Vincent T. Carpentier,
Jinquan Wong,
Youwen Yeap,
Cheryl Gan,
Peter Sutton-Smith,
Arash Badiei,
Nicola L. Fazzalari,
Julia S. Kuliwaba
et al.
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688-694
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Effect of transforming growth factor beta (TGF-β) receptor I kinase inhibitor on prostate cancer bone growth
26 December 2011
Abstract: Transforming growth factor beta 1 (TGF-β1) has been implicated in the pathogenesis of prostate cancer (PCa) bone metastasis. In this study, we tested the antitumor efficacy of a selective TG...
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Xinhai Wan,
Zhi-Gang Li,
Jonathan M. Yingling,
Jun Yang,
Michael W. Starbuck,
Murali K. Ravoori,
Vikas Kundra,
Elba Vazquez,
Nora M. Navone
et al.
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695-703
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Proteinase-activated receptor-2 is required for normal osteoblast and osteoclast differentiation during skeletal growth and repair
06 January 2012
Abstract: Proteinase-activated receptor-2 (PAR2) is a G-protein coupled receptor expressed by osteoblasts and monocytes. PAR2 is activated by a number of proteinases including coagulation factors and ...
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S.R. Georgy,
C.N. Pagel,
A. Ghasem-Zadeh,
R.M.D. Zebaze,
R.N. Pike,
N.A. Sims,
E.J. Mackie
et al.
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704-712
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Independent predictors of all osteoporosis-related fractures among healthy Saudi postmenopausal women: The CEOR Study
03 January 2012
Abstract: This study was designed to identify independent predictors of all osteoporosis-related fractures (ORFs) among healthy Saudi postmenopausal women. We prospectively followed a cohort of 707 he...
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Abdulrahim A. Rouzi,
Sharifa A. Al-Sibiani,
Nawal S. Al-Senani,
Raja M. Radaddi,
Mohammed-Salleh M. Ardawi
et al.
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713-722
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Krüppel-like factors KLF2 and 6 and Ki-67 are direct targets of zoledronic acid in MCF-7 cells
03 January 2012
Abstract: Bisphosphonates (BP) are used for the treatment of osteoporosis and bone metastases due to breast and prostate cancer. Recent clinical studies indicated a benefit in survival and tumor relap...
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Regina Ebert,
Sabine Zeck,
Jutta Meissner-Weigl,
Barbara Klotz,
Tilman D. Rachner,
Peggy Benad,
Ludger Klein-Hitpass,
Maximilian Rudert,
Lorenz C. Hofbauer,
Franz Jakob
et al.
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723-732
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The different contributions of cortical and trabecular bone to implant anchorage in a human vertebra
30 December 2011
Abstract: The quality of the peri-implant bone and the strength of the bone–implant interface are important factors for implant anchorage. With regard to peri-implant bone, cortical and trabecular com...
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Davide Ruffoni,
Andreas J. Wirth,
Juri A. Steiner,
Ian H. Parkinson,
Ralph Müller,
G. Harry van Lenthe
et al.
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733-738
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Bisphosphonate treatment of postmenopausal osteoporosis is associated with a dose dependent increase in serum sclerostin
09 January 2012
Abstract: The benefits coming from long-term treatment of postmenopausal osteoporosis with bisphophonates are limited by a coupled decrease in bone formation. The objective of this study is to determi...
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Davide Gatti,
Ombretta Viapiana,
Silvano Adami,
Luca Idolazzi,
Elena Fracassi,
Maurizio Rossini
et al.
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739-742
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Age-related loss of proximal femoral strength in elderly men and women: The Age Gene/Environment Susceptibility Study — Reykjavik
26 December 2011
Abstract: The risk of hip fracture rises rapidly with age, and is particularly high in women. This increase in fracture risk reflects both the age-related change in the risk of falling and decrements ...
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T.F. Lang,
S. Sigurdsson,
G. Karlsdottir,
D. Oskarsdottir,
A. Sigmarsdottir,
J. Chengshi,
J. Kornak,
T.B. Harris,
G. Sigurdsson,
B.Y. Jonsson,
K. Siggeirsdottir,
G. Eiriksdottir,
V. Gudnason,
J.H. Keyak
et al.
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743-748
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Ultrashort echo time (UTE) imaging with bi-component analysis: Bound and free water evaluation of bovine cortical bone subject to sequential drying
09 January 2012
Abstract: Recent proton magnetic resonance (MR) spectroscopy studies have shown that cortical bone exists as different components which have distinct transverse relaxation times (T2s). However, cortic...
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Reni Biswas,
Won Bae,
Eric Diaz,
Koichi Masuda,
Christine B. Chung,
Graeme M. Bydder,
Jiang Du
et al.
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749-755
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The emerging role of lysophosphatidic acid (LPA) in skeletal biology
30 December 2011
Abstract: Lysophosphatidic acid (LPA) is the simplest signalling lipid eliciting pleiotropic actions upon most mammalian cell types. Although LPA has an established role in many biological processes, ...
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Julia Blackburn,
Jason P. Mansell
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756-762
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Mice with increased angiogenesis and osteogenesis due to conditional activation of HIF pathway in osteoblasts are protected from ovariectomy induced bone loss
12 January 2012
Abstract: Postmenopausal osteoporosis is characterized by a reduction in the numbers of sinusoidal and arterial capillaries in the bone marrow and reduced bone perfusion suggesting a role of vascular ...
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Qiang Zhao,
Xing Shen,
Wei Zhang,
Guochun Zhu,
Jin Qi,
Lianfu Deng
et al.
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763-770
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Is the spinal motion segment a diarthrodial polyaxial joint: What a nice nucleus like you doing in a joint like this?
06 January 2012
Abstract: This review challenges an earlier view that the intervertebral joint could not be classified as a diarthrodial joint and should remain as an amphiarthrosis. However, a careful analysis of th...
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Irving M. Shapiro,
Edward J. Vresilovic,
Makarand V. Risbud
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771-776
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Variations in vertebral body dimensions in women measured by 3D-XA: A longitudinal in vivo study
12 January 2012
Abstract: Bone size and shape play an important role in bone strength, as shown by biomechanical testing and clinical studies. Vertebral body dimensions determine vertebral body strength even after ad...
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S. Kolta,
S. Kerkeni,
C. Travert,
W. Skalli,
R. Eastell,
C.C. Glüer,
C. Roux
et al.
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777-783
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Increased susceptibility to microdamage in Brtl/+ mouse model for osteogenesis imperfecta
16 January 2012
Abstract: Osteogenesis imperfecta (OI) is a genetic disease of collagen or collagen-related proteins that adversely impacts bone mass and fracture resistance. Little is known regarding the role that m...
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Mathieu S. Davis,
Bethany L. Kovacic,
Joan C. Marini,
Albert J. Shih,
Kenneth M. Kozloff
et al.
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784-791
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Modeling of cortical bone adaptation in a rat ulna: Effect of frequency
13 January 2012
Abstract: We employ a recently developed model for the adaptation of cortical bone in response to mechanical loading to study the effect of loading frequency on the computed response, and we compare o...
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N. Chennimalai Kumar,
J.A. Dantzig,
I.M. Jasiuk
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792-797
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Osteoclasts derived from patients with neurofibromatosis 1 (NF1) display insensitivity to bisphosphonates in vitro
16 January 2012
Abstract: A total of 20 patients with neurofibromatosis 1 (NF1) were screened for NF1-related osteoporosis, and blood samples were collected for isolation of peripheral blood osteoclast progenitors. P...
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Eetu Heervä,
Sirkku Peltonen,
Erkki Svedström,
Hannu T. Aro,
Kalervo Väänänen,
Juha Peltonen
et al.
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798-803
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Characterization of mesenchymal progenitor cells isolated from human bone marrow by negative selection
16 January 2012
Abstract: Studies on the pathogenesis of osteoporosis and other metabolic bone diseases would be greatly facilitated by the development of approaches to assess changes in gene expression in osteoblast...
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Ulrike I. Mödder,
Matthew M. Roforth,
Kristy M. Nicks,
James M. Peterson,
Louise K. McCready,
David G. Monroe,
Sundeep Khosla
et al.
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804-810
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| Corrigenda |
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Article Title |
Author(s) |
Pages |
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Corrigendum to “Bisphosphonates and glucocorticoid osteoporosis in men: results of a randomized controlled trial comparing zoledronic acid with risedronate” [Bone 50 (2012) 289-295]
09 January 2012
, cited in the second to last sentence in the first column of page 292, was erroneously omitted from the manuscript. The table appears below:
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Philip N. Sambrook,
Christian Roux,
Jean-Pierre Devogelaer,
Kenneth Saag,
Chak-Sing Lau,
Jean-Yves Reginster,
Christina Bucci-Rechtweg,
Guoqin Su,
David M. Reid
et al.
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811
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Corrigendum to “Effects of 50 Hz sinusoidal electromagnetic fields of different intensities on proliferation, differentiation and mineralization potentials of rat osteoblasts” [Bone 49 (2011) 753–761]
09 January 2012
In the author line, affiliation “a” and "b" was incomplete. The correct affiliation “a” and "b" appears above.
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Jian Zhou,
Lei-Guo Ming,
Bao-Feng Ge,
Jia-Qi Wang,
Rui-Qing Zhu,
Zhe Wei,
Hui-Ping Ma,
Cory J. Xian,
Ke-Ming Chen
et al.
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812
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